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Targeted Allele Detail
Symbol: Dock2tm1Ysfk
Name: dedicator of cyto-kinesis 2; targeted mutation 1, Yoshinori Fukui
MGI ID: MGI:3772945
Synonyms: DOCK2-GFP
Gene: Dock2  Location: Chr11:34226815-34783892 bp, - strand  Genetic Position: Chr11, 19.68 cM, cytoband A5
Germline Transmission:  Earliest citation of germline transmission: J:113266
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsGFP and a neo cassette were inserted immediately following the last exon. The neo cassette was removed by germline, cre-mediated recombination. (J:113266)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dock2 Mutation:  86 strains or lines available
Original:  J:113266 Kunisaki Y, et al., DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis. J Cell Biol. 2006 Aug 28;174(5):647-52
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory