Dock2^tm1Ysfk
Targeted Allele Detail

Summary

• Symbol: Dock2^tm1Ysfk
• Name: dedicator of cyto-kinesis 2; targeted mutation 1, Yoshinori Fukui
• MGI ID: MGI:3772945
• Synonyms: DOCK2-GFP
• Gene: Dock2 Location: Chr11:34176815-34674719 bp, - strand Genetic Position: Chr11, 19.68 cM, cytoband A5
• Alliance: Dock2^tm1Ysfk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:113266
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: GFP and a neo cassette were inserted immediately following the last exon. The neo cassette was removed by germline, cre-mediated recombination. (J:113266)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dock2 Mutation: 142 strains or lines available

References

• Original: J:113266 Kunisaki Y, et al., DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis. J Cell Biol. 2006 Aug 28;174(5):647-52
• All: 9 reference(s)