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Transgene Detail
Symbol: Tg(tetO-Clockm1Jt)CL57Jt
Name: transgene insertion CL57, Joseph S Takahashi
MGI ID: MGI:3772924
Synonyms: tetO::Clockdelta 19
Transgene: Tg(tetO-Clockm1Jt)CL57Jt  Location: unknown  
Strain of Origin:  CD-1
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Mutation:    Insertion
Tg(tetO-Clockm1Jt)CL57Jt expresses 1 gene
Mutation detailsA transgenic vector was designed to carry the full-length Clockdelta19 mutant gene downstream of a tetracycline-responsive promoter (TRE; tetO). Crossing these mice with mice expressing the tTA or reverse tetracycline-controlled transactivator protein under control of tissue-specific promoters, transgene expression can be regulated in appropriate tissues in the offspring with administration of the tet analog doxycycline. (J:120326)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:120326 Hong HK, et al., Inducible and reversible Clock gene expression in brain using the tTA system for the study of circadian behavior. PLoS Genet. 2007 Feb 23;3(2):e33
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
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