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Xisttm4Sado
Targeted Allele Detail
Nomenclature
Symbol: Xisttm4Sado
Name: inactive X specific transcripts; targeted mutation 4, Takashi Sado
MGI ID: MGI:3772876
Synonyms: XistIVS
Gene: Xist  Location: ChrX:103460373-103483233 bp, - strand  Genetic Position: ChrX, 46.15 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130425
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA splice donor and splice acceptor was inserted into exon 4. The absence of transcript expression was confirmed by RT-PCR. (J:130425)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Xist Mutation:  5 strains or lines available
References
Original:  J:130425 Ohhata T, et al., Crucial role of antisense transcription across the Xist promoter in Tsix-mediated Xist chromatin modification. Development. 2008 Jan;135(2):227-35
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory