Tor1a^tm2Yql
Targeted Allele Detail

Summary

• Symbol: Tor1a^tm2Yql
• Name: torsin family 1, member A (torsin A); targeted mutation 2, Yuqing Li
• MGI ID: MGI:3772564
• Synonyms: Dyt1 loxP
• Gene: Tor1a Location: Chr2:30850639-30857945 bp, - strand Genetic Position: Chr2, 21.77 cM
• Alliance: Tor1a^tm2Yql page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130483
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt-flanked neo cassette with a 5' loxP site was inserted into intron 4 and an additional loxP site was inserted into intron 2. The neo cassette was removed by flp-mediated recombination. (J:130483)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tor1a Mutation: 22 strains or lines available

References

• Original: J:130483 Yokoi F, et al., Motor Deficits and Hyperactivity in Cerebral Cortex-specific Dyt1 Conditional Knockout Mice. J Biochem. 2008 Jan;143(1):39-47
• All: 10 reference(s)