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Il13ra1tm1Twy
Targeted Allele Detail
Nomenclature
Symbol: Il13ra1tm1Twy
Name: interleukin 13 receptor, alpha 1; targeted mutation 1, Thomas A Wynn
MGI ID: MGI:3772443
Synonyms: Il13ra1-
Gene: Il13ra1  Location: ChrX:36112110-36171259 bp, + strand  Genetic Position: ChrX, 20.49 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130488
Parent Cell Line:  F1H4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NTac)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 through 4 were replaced with a transmembrane lacZ cassette and a floxed neo cassette. The absence of transcript was confirmed by RT-PCR followed by endpoint PCR on lung fibroblasts. (J:130488)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il13ra1 Mutation:  7 strains or lines available
References
Original:  J:130488 Ramalingam TR, et al., Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor alpha1 chain. Nat Immunol. 2008 Jan;9(1):25-33
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory