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Fgfrl1tm1True
Targeted Allele Detail
Nomenclature
Symbol: Fgfrl1tm1True
Name: fibroblast growth factor receptor-like 1; targeted mutation 1, Beat Trueb
MGI ID: MGI:3771861
Synonyms: Fgfrl1-
Gene: Fgfrl1  Location: Chr5:108694229-108706950 bp, + strand  Genetic Position: Chr5, 53.24 cM, cytoband E3-F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130254
Parent Cell Line:  iTL1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA DNA segement stretching from within the promoter to intron 1 was replaced with a neo cassette. The absence of transcript containing exon 1 and the presence of a transcript containing the neo cassette was confirmed by northern blot analysis. (J:130254)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfrl1 Mutation:  4 strains or lines available
References
Original:  J:130254 Baertschi S, et al., Mice with a targeted disruption of the Fgfrl1 gene die at birth due to alterations in the diaphragm. FEBS J. 2007 Dec;274(23):6241-53
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/17/2015
MGI 5.21
The Jackson Laboratory