About   Help   FAQ
Ube3atm2Alb
Targeted Allele Detail
Nomenclature
Symbol: Ube3atm2Alb
Name: ubiquitin protein ligase E3A; targeted mutation 2, Arthur L Beaudet
MGI ID: MGI:3771814
Synonyms: Ube3aYFP
Gene: Ube3a  Location: Chr7:59228750-59310837 bp, + strand  Genetic Position: Chr7, 33.95 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130068
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
 
Mutation detailsExon 10 was fused to YFP and a floxed neo cassette was inserted downstream of it to produce expression of YFP that recapitulates endogenous expression. (J:130068)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ube3a Mutation:  17 strains or lines available
References
Original:  J:130068 Dindot SV, et al., The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology. Hum Mol Genet. 2008 Jan 1;17(1):111-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/06/2021
MGI 6.16
The Jackson Laboratory