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Targeted Allele Detail
Symbol: Ube3atm2Alb
Name: ubiquitin protein ligase E3A; targeted mutation 2, Arthur L Beaudet
MGI ID: MGI:3771814
Synonyms: Ube3aYFP
Gene: Ube3a  Location: Chr7:59228750-59310837 bp, + strand  Genetic Position: Chr7, 33.95 cM
Germline Transmission:  Earliest citation of germline transmission: J:130068
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
Mutation detailsExon 10 was fused to YFP and a floxed neo cassette was inserted downstream of it to produce expression of YFP that recapitulates endogenous expression. (J:130068)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ube3a Mutation:  17 strains or lines available
Original:  J:130068 Dindot SV, et al., The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology. Hum Mol Genet. 2008 Jan 1;17(1):111-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory