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Rpe65tm1Lrcb
Targeted Allele Detail
Nomenclature
Symbol: Rpe65tm1Lrcb
Name: retinal pigment epithelium 65; targeted mutation 1, Christian Grimm
MGI ID: MGI:3771723
Synonyms: R91W, Rpe65R91W
Gene: Rpe65  Location: Chr3:159599233-159624799 bp, + strand  Genetic Position: Chr3, 82.52 cM, cytoband H4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130076
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rpe65 Mutation:  4 strains or lines available
References
Original:  J:130076 Samardzija M, et al., R91W mutation in Rpe65 leads to milder early-onset retinal dystrophy due to the generation of low levels of 11-cis-retinal. Hum Mol Genet. 2008 Jan 15;17(2):281-92
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory