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Targeted Allele Detail
Symbol: Arid5btm1Whit
Name: AT rich interactive domain 5B (MRF1-like); targeted mutation 1, Robert H Whitson
MGI ID: MGI:3771593
Synonyms: Mrf-2-
Gene: Arid5b  Location: Chr10:68092520-68278740 bp, - strand  Genetic Position: Chr10, 35.14 cM, cytoband B5.1
Germline Transmission:  Earliest citation of germline transmission: J:130390
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S1
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 5 was replaced with a neo cassette. This exon encodes for the third and fourth helices of the ARID structure. The absence of trascript was confirmed by northern blot analysis on extracts from the heart. (J:130390)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arid5b Mutation:  108 strains or lines available
Original:  J:130390 Whitson RH, et al., Neonatal mortality and leanness in mice lacking the ARID transcription factor Mrf-2. Biochem Biophys Res Commun. 2003 Dec 26;312(4):997-1004
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory