About   Help   FAQ
Gsk3atm1.1Jrw
Targeted Allele Detail
Summary
Symbol: Gsk3atm1.1Jrw
Name: glycogen synthase kinase 3 alpha; targeted mutation 1.1, James R Woodgett
MGI ID: MGI:3771223
Synonyms: Gak3a-
Gene: Gsk3a  Location: Chr7:24927683-24937276 bp, - strand  Genetic Position: Chr7, 13.73 cM
Alliance: Gsk3atm1.1Jrw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130033
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 2 was removed by germ-line, cre-mediated recombination. The absence of protein product was confirmed by western blot analysis on brain, liver, spleen and testes extracts. (J:130033)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gsk3a Mutation:  18 strains or lines available
References
Original:  J:130033 MacAulay K, et al., Glycogen synthase kinase 3alpha-specific regulation of murine hepatic glycogen metabolism. Cell Metab. 2007 Oct;6(4):329-37
All:  25 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/12/2024
MGI 6.23
The Jackson Laboratory