Gpihbp1^tm1Sgy
Targeted Allele Detail

Summary

• Symbol: Gpihbp1^tm1Sgy
• Name: GPI-anchored HDL-binding protein 1; targeted mutation 1, Stephen G Young
• MGI ID: MGI:3771171
• Synonyms: Gpihbp1^-, Gpihbp1^tm1Sgyo
• Gene: Gpihbp1 Location: Chr15:75468479-75470062 bp, + strand Genetic Position: Chr15, 34.59 cM, cytoband E1
• Alliance: Gpihbp1^tm1Sgy page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:129764
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame was replaced with a lacZ-neo cassette. The absence of protein product was confirmed by western blot analysis on gonadal fat and brown adipose tissue extracts. However, no beta-galactosidase activity could be detected. (J:129764)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpihbp1 Mutation: 19 strains or lines available

References

• Original: J:129764 Beigneux AP, et al., Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. Cell Metab. 2007 Apr;5(4):279-91
• All: 23 reference(s)