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Sec14l2tm1Arai
Targeted Allele Detail
Nomenclature
Symbol: Sec14l2tm1Arai
Name: SEC14-like lipid binding 2; targeted mutation 1, Hiroyuki Arai
MGI ID: MGI:3771069
Synonyms: Spf-
Gene: Sec14l2  Location: Chr11:4097039-4123415 bp, - strand  Genetic Position: Chr11, 2.87 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:129749
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 3 and 4 were replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on hepatic extracts. (J:129749)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sec14l2 Mutation:  10 strains or lines available
References
Original:  J:129749 Shibata N, et al., Regulation of hepatic cholesterol synthesis by a novel protein (SPF) that accelerates cholesterol biosynthesis. FASEB J. 2006 Dec;20(14):2642-4
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory