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Cadm1tm1Momo
Targeted Allele Detail
Summary
Symbol: Cadm1tm1Momo
Name: cell adhesion molecule 1; targeted mutation 1, Takashi Momoi
MGI ID: MGI:3769418
Synonyms: Ra175-, SynCAM 1 KO
Gene: Cadm1  Location: Chr9:47441471-47769413 bp, + strand  Genetic Position: Chr9, 25.83 cM, cytoband B-C
Alliance: Cadm1tm1Momo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:129496
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 and part of intron 1 were replaced with a lacZ-neo cassette. X-galactosidase staining was performed to confirm lacZ expression. (J:129496)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Cadm1 Mutation:  31 strains or lines available
References
Original:  J:129496 Fujita E, et al., Oligo-astheno-teratozoospermia in mice lacking RA175/TSLC1/SynCAM/IGSF4A, a cell adhesion molecule in the immunoglobulin superfamily. Mol Cell Biol. 2006 Jan;26(2):718-26
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory