Frs2tm1Fwan
Targeted Allele Detail
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Symbol: |
Frs2tm1Fwan |
Name: |
fibroblast growth factor receptor substrate 2; targeted mutation 1, Fen Wang |
MGI ID: |
MGI:3768912 |
Synonyms: |
Frs2alphaflox, Frs2alphafloxneo |
Gene: |
Frs2 Location: Chr10:116905332-116984439 bp, - strand Genetic Position: Chr10, 65.09 cM
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Alliance: |
Frs2tm1Fwan page
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Germline Transmission: |
Earliest citation of germline transmission:
J:128712
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: Exon 5 was flanked by loxP sites with one loxP site placed immediately upstream and the other placed 600 bp downstream. A FRT-flanked neo selection cassette was placed between the exon and the downstream loxP site. Mice were crossed with FLP expressing knock-in mice to remove the neo cassette. Insertion of the loxP sites were presumed not to effect gene expression because homozygote mice were born at Mendelian frequencies.
(J:128712)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Frs2 Mutation: |
64 strains or lines available
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Original: |
J:128712 Lin Y, et al., Generation of an Frs2alpha conditional null allele. Genesis. 2007 Sep;45(9):554-9 |
All: |
26 reference(s) |
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