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Targeted Allele Detail
Symbol: Pdgfctm1.1Hdin
Name: platelet-derived growth factor, C polypeptide; targeted mutation 1.1, Hao Ding
MGI ID: MGI:3768438
Synonyms: Pdgf-cdeltaexon5
Gene: Pdgfc  Location: Chr3:81036416-81214040 bp, + strand  Genetic Position: Chr3, 35.73 cM
Cleft palate and subepithelial blister in the nasal septum of Pdgfctm1.1Hdin/Pdgfctm1.1Hdin mutants

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:128709
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsExon 5 was removed by cre-mediated recombination. The absence of transcript was confirmed by northern blot analysis on embryos. (J:128709)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pdgfc Mutation:  23 strains or lines available
Original:  J:128709 Wu X, et al., Generation of conditional knockout alleles for PDGF-C. Genesis. 2007 Oct;45(10):653-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory