Tent2^tm1Tomo
Targeted Allele Detail

Summary

• Symbol: Tent2^tm1Tomo
• Name: terminal nucleotidyltransferase 2; targeted mutation 1, Tomoko Nakanishi
• MGI ID: MGI:3767669
• Synonyms: mGLD-2^-
• Gene: Tent2 Location: Chr13:93282790-93328893 bp, - strand Genetic Position: Chr13, 47.81 cM
• Alliance: Tent2^tm1Tomo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:128466
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced by a neo cassette. The absence of protein was confirmed by western blot analysis on liver tissue. (J:128466)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tent2 Mutation: 38 strains or lines available

References

• Original: J:128466 Nakanishi T, et al., Disruption of mouse poly(A) polymerase mGLD-2 does not alter polyadenylation status in oocytes and somatic cells. Biochem Biophys Res Commun. 2007 Dec 7;364(1):14-9
• All: 1 reference(s)