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Paxip1tm2Gdr
Targeted Allele Detail
Nomenclature
Symbol: Paxip1tm2Gdr
Name: PAX interacting (with transcription-activation domain) protein 1; targeted mutation 1, Gregory R Dressler
MGI ID: MGI:3767658
Synonyms: ptipfl, PTIPflox, ptiploxP
Gene: Paxip1  Location: Chr5:27740667-27791339 bp, - strand  Genetic Position: Chr5, 13.23 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:128440
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA neo cassette flanked by FRT sites was inserted upstream of exon 1 and an additional loxP site was inserted downstream of exon 1. The neo cassette was subsequently removed by flp-mediated recombination. (J:128440, J:148599)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Paxip1 Mutation:  7 strains or lines available
References
Original:  J:128440 Patel SR, et al., The BRCT-domain containing protein PTIP links PAX2 to a histone H3, lysine 4 methyltransferase complex. Dev Cell. 2007 Oct;13(4):580-92
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/21/2015
MGI 5.21
The Jackson Laboratory