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Fbxw7tm1.1Kei
Targeted Allele Detail
Nomenclature
Symbol: Fbxw7tm1.1Kei
Name: F-box and WD-40 domain protein 7; targeted mutation 1.1, Keiichi Nakayama
MGI ID: MGI:3767578
Synonyms: Fbxw7deltaE5
Gene: Fbxw7  Location: Chr3:84815268-84979198 bp, + strand  Genetic Position: Chr3, 37.7 cM, cytoband E3.3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:128523
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    Germline cre-mediated recombination was used to remove the floxed exon 5. (J:128523)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fbxw7 Mutation:  48 strains or lines available
References
Original:  J:128523 Onoyama I, et al., Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis. J Exp Med. 2007 Nov 26;204(12):2875-88
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory