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Celf3tm1Ade
Targeted Allele Detail
Nomenclature
Symbol: Celf3tm1Ade
Name: CUGBP, Elav-like family member 3; targeted mutation 1, Arvind Dev
MGI ID: MGI:3767553
Synonyms: Brunol1-
Gene: Celf3  Location: Chr3:94478295-94492198 bp, + strand  Genetic Position: Chr3, 40.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:128362
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA pgk-neo cassette replaced exons 3 - 12 via homologous recombination. Northern blot and RT-PCR analysis of testes confirmed the absence of transcript in homozygous mice. (J:128362)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 10 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Celf3 Mutation:  10 strains or lines available
References
Original:  J:128362 Dev A, et al., Mice deficient for RNA-binding protein brunol1 show reduction of spermatogenesis but are fertile. Mol Reprod Dev. 2007 Nov;74(11):1456-64
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory