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Transgene Detail
Symbol: Tg(Thy1-EGFP)MJrs
Name: transgene insertion M, Joshua R Sanes
MGI ID: MGI:3766828
Synonyms: GFP line-M, GFP-M, Thy1-GFP line M, Thy1-GFPM, Thy1-GFP/M, Thy1::GFP-M
Transgene: Tg(Thy1-EGFP)MJrs  Location: unknown  
Strain of Origin:  (C57BL/6J x CBA)F1
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsThe Thy1-GFP transgene was designed with a modified regulatory region of the "murine thy1.2 gene" (extending from the promoter to the intron following exon 4, excluding exon 3 and its flanking introns) upstream of an enhanced green fluorescent protein (EGFP) sequence. Line M was subsequently established and analyzed. Expression of EGFP is detected primarily in mossy fibers in internal granule layer of the cerebellum (10-80% incidence). Less than 10% of all motor axons, retinal ganglion cells, lumbar dorsal root ganglion, and cortex express EGFP, with no reported expression in other tested neuronal tissues. (J:93699)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:93699 Feng G, et al., Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron. 2000 Oct;28(1):41-51
All:  100 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
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