About   Help   FAQ
Targeted Allele Detail
Symbol: Eno2tm1(DTA)Hsak
Name: enolase 2, gamma neuronal; targeted mutation 1, Hitoshi Sakno
MGI ID: MGI:3765961
Synonyms: Eno2-STOP-DTA, NSE-DTA
Gene: Eno2  Location: Chr6:124760053-124769673 bp, - strand  Genetic Position: Chr6, 59.17 cM
Ablation of medium-spiny projection neurons in the striatum of Gng7tm2(cre/PGR)Mmsh/Gng7+ Eno2tm1(DTA)Hsak/Eno2+ mice

Show the 1 phenotype image(s) involving this allele.

Germline Transmission:  Earliest citation of germline transmission: J:127822
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence)
Mutation:    Insertion
Mutation detailsA cre-inducible death cassette consisting of a loxP flanked stop codon upstream of a diphtheria toxin A coding sequence was introduced into the gene locus. Expression of cre recombinase will excise the stop codon leading to death of the cell. (J:127822)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Eno2 Mutation:  3 strains or lines available
Original:  J:127822 Kobayakawa K, et al., Innate versus learned odour processing in the mouse olfactory bulb. Nature. 2007 Nov 22;450(7169):503-8
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.14
The Jackson Laboratory