Eno2^tm1(DTA)Hsak
Targeted Allele Detail

Summary

• Symbol: Eno2^tm1(DTA)Hsak
• Name: enolase 2, gamma neuronal; targeted mutation 1, Hitoshi Sakno
• MGI ID: MGI:3765961
• Synonyms: Eno2-STOP-DTA, NSE-DTA
• Gene: Eno2 Location: Chr6:124737018-124746489 bp, - strand Genetic Position: Chr6, 59.17 cM
• Alliance: Eno2^tm1(DTA)Hsak page

Ablation of medium-spiny projection neurons in the striatum of Gng7^{tm2(cre/PGR)Mmsh}/Gng7⁺ Eno2^tm1(DTA)Hsak/Eno2⁺ mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:127822
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A cre-inducible death cassette consisting of a loxP flanked stop codon upstream of a diphtheria toxin A coding sequence was introduced into the gene locus. Expression of cre recombinase will excise the stop codon leading to death of the cell. (J:127822)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Eno2 Mutation: 53 strains or lines available

References

• Original: J:127822 Kobayakawa K, et al., Innate versus learned odour processing in the mouse olfactory bulb. Nature. 2007 Nov 22;450(7169):503-8
• All: 18 reference(s)