Tg(Nes-cre/Esr1*)4Ynj
Transgene Detail

Summary

• Symbol: Tg(Nes-cre/Esr1*)4Ynj
• Name: transgene insertion 4, Yuh-Nung Jan
• MGI ID: MGI:3765946
• Synonyms: nestin-creER^tm, Tg(Nes-cre/Esr1)4Ynj
• Transgene: Tg(Nes-cre/Esr1*)4Ynj Location: unknown
• Alliance: Tg(Nes-cre/Esr1*)4Ynj page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Nes-cre/Esr1*)4Ynj expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Nes (25491)

  Nes	(MGI:101784)

• Mutation details: The targeting construct contains the tamoxifen-inducible cre/Esr1 sequence under the control of the rat Nestin promoter. Line 4 shows postnatally inducible cre activity, in addition to inducible embryonic brain and spinal cord activity assayed by crossing the mice to mice carrying the ROSA26 reporter. (J:127227)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nes (rat) Summary of all recombinase alleles driven by Nes. Comparative matrix view of recombinase activities Alliance rat Nes gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:127227 Kuo CT, et al., Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. Cell. 2006 Dec 15;127(6):1253-64
• All: 19 reference(s)