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Gt(ROSA)26Sortm2(cre/ERT2)Brn
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm2(cre/ERT2)Brn
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Anton Berns
MGI ID: MGI:3764519
Synonyms: ERT2, Gt(ROSA)26Sortm2(cre/Esr1)Brn, Rosa26CreERT2, ROSA26-CreERT2
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077333 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:127226
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    induced by tamoxifen
Mutation:    Insertion
 
Mutation details
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gt(ROSA)26Sor     Summary of all recombinase alleles driven by Gt(ROSA)26Sor.
 

Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  253 strains or lines available
References
Original:  J:127226 Hameyer D, et al., Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues. Physiol Genomics. 2007 Sep 19;31(1):32-41
All:  27 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory