About   Help   FAQ
Ptch1tm1Hahn
Targeted Allele Detail
Nomenclature
Symbol: Ptch1tm1Hahn
Name: patched homolog 1; targeted mutation 1, Heidi Hahn
MGI ID: MGI:3764517
Synonyms: Ptchflox
Gene: Ptch1  Location: Chr13:63508328-63573598 bp, - strand  Genetic Position: Chr13, 32.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:127207
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted into intron 7 and a second loxP site followed by a frt-flanked neo cassette was inserted into intron 9. Insertion was confirmed by Southern blot analysis and PCR genotyping. (J:127207)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptch1 Mutation:  21 strains or lines available
References
Original:  J:127207 Uhmann A, et al., The Hedgehog receptor Patched controls lymphoid lineage commitment. Blood. 2007 Sep 15;110(6):1814-23
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/25/2015
MGI 5.21
The Jackson Laboratory