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Cyp3a13tm1Ahs
Targeted Allele Detail
Nomenclature
Symbol: Cyp3a13tm1Ahs
Name: cytochrome P450, family 3, subfamily a, polypeptide 13; targeted mutation 1, Alfred H Schinkel
MGI ID: MGI:3764486
Synonyms: Cyp3a-
Gene: Cyp3a13  Location: Chr5:137892932-137921619 bp, - strand  Genetic Position: Chr5, 76.89 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:127366
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1, exon 2 and the putative promoter region were replaced with a PGK-hygromycin cassette. Authors state that this is a null allele. (J:127366)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Cyp3a13 Mutation:  16 strains or lines available
References
Original:  J:127366 van Herwaarden AE, et al., Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism. J Clin Invest. 2007 Nov;117(11):3583-92
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory