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Tg(Thy1-Syt1/ECFP)1Sud
Transgene Detail
Nomenclature
Symbol: Tg(Thy1-Syt1/ECFP)1Sud
Name: transgene insertion 1, Thomas C Sudhof
MGI ID: MGI:3762948
Synonyms: Syt1 transgenic, Tg(Thy1-Syt1-ECFP)1Sud, TMC
Transgene: Tg(Thy1-Syt1/ECFP)1Sud  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA transgenic vector was designed to create a rat synaptotagmin 1/enhanced cyan fluorescent protein (ECFP) fusion protein under the control of a mouse Thy1 promoter lacking exon3 and the flanking introns (to make gene expression neuron-specific). Expression is detected only in the brain with fluorescence observed throughout the brain, marking synaptic vesicles. (J:105052)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:105052 Han W, et al., C-terminal ECFP fusion impairs synaptotagmin 1 function: crowding out synaptotagmin 1. J Biol Chem. 2005 Feb 11;280(6):5089-100
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory