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Git1Gt(FHCRC-GT-S10-12C1)Sor
Gene trapped Allele Detail
Nomenclature
Symbol: Git1Gt(FHCRC-GT-S10-12C1)Sor
Name: G protein-coupled receptor kinase-interactor 1; gene trap FHCRC-GT-S10-12C1, Philippe Soriano
MGI ID: MGI:3762634
Synonyms: GIT1-
Gene: Git1  Location: Chr11:77493562-77507786 bp, + strand  Genetic Position: Chr11, 46.61 cM
Mutation
origin
Mutant Cell Line:  S10-12C1
Germline Transmission:  Earliest citation of germline transmission: J:126878
Parent Cell Line:  AK7.1 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: ROSAFARY
 
Mutation detailsThe gene trap vector containing a beta-geo cassette and a PGK-hygro cassette was inserted into intron 1. Insertion was confirmed by genomic PCR and expression of the lacZ cassette was confirmed by beta-galactosidase staining. (J:126878)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Git1 Mutation:  31 strains or lines available
References
Original:  J:126878 Schmalzigaug R, et al., Differential expression of the ARF GAP genes GIT1 and GIT2 in mouse tissues. J Histochem Cytochem. 2007 Oct;55(10):1039-48
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/12/2018
MGI 6.12
The Jackson Laboratory