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Tg(Nphs1-cre)33Mska
Transgene Detail
Nomenclature
Symbol: Tg(Nphs1-cre)33Mska
Name: transgene insertion 33, Taiji Matsusaka
MGI ID: MGI:3762483
Synonyms: Nphs1-Cre
Transgene: Tg(Nphs1-cre)33Mska  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1 x C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe cre recombinase cDNA was combined with a 5.5kb mouse Nphs1 promoter fragment and intron of the rabbit beta-globin gene. The construct was injected into fertilized eggs from (C57BL/6 x DBA/2) x C57BL/6N mice. Cre mRNA was detected in the kidney by Northern blot in five lines, and Cre protein was detected in podocytes by immunohistochemistry in four lines. Line 33 was established by backcrossing to C57BL/6N mice. (J:126591)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nphs1     Summary of all recombinase alleles driven by Nphs1. Comparative matrix view of recombinase activities
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:126591 Asano T, et al., Permanent genetic tagging of podocytes: fate of injured podocytes in a mouse model of glomerular sclerosis. J Am Soc Nephrol. 2005 Aug;16(8):2257-62
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory