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Tg(KRT14-Il1f6)1Hblu
Transgene Detail
Nomenclature
Symbol: Tg(KRT14-Il1f6)1Hblu
Name: transgene insertion 1, Hal Blumberg
MGI ID: MGI:3762035
Transgene: Tg(KRT14-Il1f6)1Hblu  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe promoter of human KRT14 drives the expression of mouse Il1f5 in basal keratinocytes. At least 70-fold higher mRNA expression compared to in wild-type was detected in mice expressing this transgene. (J:126327)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
9 founders were used to create 4 lines with at least 70-fold higher mRNA expression.

References
Original:  J:126327 Blumberg H, et al., Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation. J Exp Med. 2007 Oct 29;204(11):2603-14
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory