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Ntsr1tm2Dgen
Targeted Allele Detail
Nomenclature
Symbol: Ntsr1tm2Dgen
Name: neurotensin receptor 1; targeted mutation 1, Deltagen
MGI ID: MGI:3761722
Synonyms: NTR1-
Gene: Ntsr1  Location: Chr2:180499976-180544980 bp, + strand  Genetic Position: Chr2, 103.04 cM, cytoband H1-H4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:126020
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA null allele was create by deleting 457 nucleotides including the initiator methionine at nucleotide position 8 and inserting of a neo cassette. RT-PCR and immunohistochemistry were used to confirm the absence of a transcript. (J:126020)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ntsr1 Mutation:  13 strains or lines available
References
Original:  J:126020 Pettibone DJ, et al., The effects of deleting the mouse neurotensin receptor NTR1 on central and peripheral responses to neurotensin. J Pharmacol Exp Ther. 2002 Jan;300(1):305-13
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory