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Mapk8ip2tm1Rjd
Targeted Allele Detail
Nomenclature
Symbol: Mapk8ip2tm1Rjd
Name: mitogen-activated protein kinase 8 interacting protein 2; targeted mutation 1, Roger J Davis
MGI ID: MGI:3759989
Synonyms: Jip2-
Gene: Mapk8ip2  Location: Chr15:89453913-89464468 bp, + strand  Genetic Position: Chr15, 44.92 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:125318
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 3 and 4 of the coding region were replaced with a neo cassette to create a null allele. Absence of a protein product was confirmed by western blot anaysis on protein extracts on brain lysates. (J:125318)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk8ip2 Mutation:  13 strains or lines available
References
Original:  J:125318 Kennedy NJ, et al., Requirement of JIP scaffold proteins for NMDA-mediated signal transduction. Genes Dev. 2007 Sep 15;21(18):2336-46
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory