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Nup98tm1Jvd
Targeted Allele Detail
Nomenclature
Symbol: Nup98tm1Jvd
Name: nucleoporin 98; targeted mutation 1, Jan M A van Deursen
MGI ID: MGI:3759762
Synonyms: NUP98-
Gene: Nup98  Location: Chr7:102119398-102210176 bp, - strand  Genetic Position: Chr7, 54.71 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:125571
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 3 encoding amino acids 33 through 118 and part of intron 3 were replaced with a PGK-neo cassette. The absence of protein product was confirmed by quantitative western blot analysis using the alphaNUP98(151-221) antibody. (J:125571)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nup98 Mutation:  109 strains or lines available
References
Original:  J:125571 Wu X, et al., Disruption of the FG nucleoporin NUP98 causes selective changes in nuclear pore complex stoichiometry and function. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3191-6
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory