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Targeted Allele Detail
Symbol: Dmbx1tm1Sse
Name: diencephalon/mesencephalon homeobox 1; targeted mutation 1, Susumu Seino
MGI ID: MGI:3759315
Synonyms: Dmbx1-
Gene: Dmbx1  Location: Chr4:115915119-115939926 bp, - strand  Genetic Position: Chr4, 53.07 cM
Germline Transmission:  Earliest citation of germline transmission: J:125193
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsPart of exon 3 and all of exon 4 were replaced with a lacZ-neo cassette. Absence of transcript was confirmed by northern blot on E10.5 whole embryos with a probe corresponding to nucleotids +238 to +1082 of GenBank accession no. NM_130865. (J:125193)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dmbx1 Mutation:  9 strains or lines available
Original:  J:125193 Fujimoto W, et al., Dmbx1 is essential in agouti-related protein action. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15514-9
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.03
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