Gucy2d^tm1Mom
Targeted Allele Detail

Summary

• Symbol: Gucy2d^tm1Mom
• Name: guanylate cyclase 2d; targeted mutation 1, Peter Mombaerts
• MGI ID: MGI:3758883
• Synonyms: GCD-ITL
• Gene: Gucy2d Location: Chr7:98089623-98126685 bp, + strand Genetic Position: Chr7, 53.86 cM
• Alliance: Gucy2d^tm1Mom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:125485
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: An IRES-tauLacZ cassette was inserted just downstream of the endogenous coding sequence to produce bicistronic expression of the reporter and endogenous gene.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gucy2d Mutation: 42 strains or lines available

References

• Original: J:125485 Walz A, et al., Axonal wiring of guanylate cyclase-D-expressing olfactory neurons is dependent on neuropilin 2 and semaphorin 3F. Development. 2007;134:4063-72
• All: 1 reference(s)