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Ripply2tm1.1Ysa
Targeted Allele Detail
Nomenclature
Symbol: Ripply2tm1.1Ysa
Name: ripply transcriptional repressor 2; targeted mutation 1, Yumiko Saga
MGI ID: MGI:3758856
Synonyms: Ripply2-
Gene: Ripply2  Location: Chr9:87015537-87019917 bp, + strand  Genetic Position: Chr9, 46.69 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123846
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector with a floxed neo cassette replaced a portion of exon 1, introducing a termination codon right after the second translational initiation codon and creating a null allele. The floxed neo was excised by breeding the mice with transgenic mice expressing CAG-Cre. (J:123846)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 36 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ripply2 Mutation:  6 strains or lines available
References
Original:  J:123846 Morimoto M, et al., The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite. Development. 2007 Apr;134(8):1561-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory