Il20rb^tm1Dnax
Targeted Allele Detail

Summary

• Symbol: Il20rb^tm1Dnax
• Name: interleukin 20 receptor beta; targeted mutation 1, DNAX Research Institute of Cellular and Molecular Biology
• MGI ID: MGI:3757693
• Synonyms: Il20-R2^-, IL20R2tm1Dnax
• Gene: Il20rb Location: Chr9:100339772-100368526 bp, - strand Genetic Position: Chr9, 52.66 cM
• Alliance: Il20rb^tm1Dnax page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:124591
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The transcription start site and leader sequence from exon 1 and a portion of intron 1 were replaced with a LacZ-neo cassette. (J:124591)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il20rb Mutation: 31 strains or lines available

References

• Original: J:124591 Chan JR, et al., IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J Exp Med. 2006 Nov 27;203(12):2577-87
• All: 1 reference(s)