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Targeted Allele Detail
Symbol: Olfr151tm35(Adrb2)Mom
Name: olfactory receptor 151; targeted mutation 35, Peter Mombaerts
MGI ID: MGI:3722388
Synonyms: beta2AR->M71-IRES-tauGFP
Gene: Olfr151  Location: Chr9:37641273-37642357 bp, - strand  Genetic Position: Chr9, 20.8 cM
Germline Transmission:  Earliest citation of germline transmission: J:203483
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Inserted expressed sequence, Reporter)
Mutations:    Insertion, Intragenic deletion
Olfr151tm35(Adrb2)Mom expresses 1 gene
Mutation detailsThe endogenous coding sequence for this olfactory receptor was replaced with the coding sequence for beta 2 adrenergic receptor with an IRES-tauGFP-ANCF cassette inserted 3 nucleotides after the stop codon to yield bicistronic expression of beta 2 adrenergic receptor and GFP in place of this olfactory receptor. The ACNf neomycin selection cassette self-excised during transmission through the male germline leaving a single loxP site. (J:203483)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Olfr151 Mutation:  61 strains or lines available
Original:  J:203483 Brennan DJ, et al., Serum HE4 as a prognostic marker in endometrial cancer--a population based study. Gynecol Oncol. 2014 Jan;132(1):159-65
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory