About   Help   FAQ
Nlrc4tm1Gln
Targeted Allele Detail
Nomenclature
Symbol: Nlrc4tm1Gln
Name: NLR family, CARD domain containing 4; targeted mutation 1, Jorge E Galan
MGI ID: MGI:3722152
Synonyms: ipaf-
Gene: Nlrc4  Location: Chr17:74426295-74459108 bp, - strand  Genetic Position: Chr17, 45.64 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:124378
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA targeting vector inserted the IRES/nls-lacZ/MC1neo cassette to replace exons 2 and 3. RT-PCR confirmed absence of transcript in mutants. (J:124378)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nlrc4 Mutation:  38 strains or lines available
References
Original:  J:124378 Lara-Tejero M, et al., Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis. J Exp Med. 2006 Jun 12;203(6):1407-12
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory