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Tshz1tm1Core
Targeted Allele Detail
Nomenclature
Symbol: Tshz1tm1Core
Name: teashirt zinc finger family member 1; targeted mutation 1, Nathalie Core
MGI ID: MGI:3721421
Gene: Tshz1  Location: Chr18:84011627-84086404 bp, - strand  Genetic Position: Chr18, 57.53 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:124124
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 2 was replaced with a EGFP gene and a neomycin selection cassette. No gene expression was detected by in site hybridization in embryos at mid embryogenesis. EGFP protein was not detected due to a mutation that prematurely inserted a stop codon. (J:124124)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tshz1 Mutation:  16 strains or lines available
References
Original:  J:124124 Core N, et al., Tshz1 is required for axial skeleton, soft palate and middle ear development in mice. Dev Biol. 2007 Aug 15;308(2):407-20
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory