About   Help   FAQ
Tg(Itgax-cre,-EGFP)4097Ach
Transgene Detail
Nomenclature
Symbol: Tg(Itgax-cre,-EGFP)4097Ach
Name: transgene insertion 4097, Alexander V Chervonsky
MGI ID: MGI:3720729
Synonyms: CD11c-Cre, CD11c-Cre 4907, CD11c-Cre-GFP, CD11c-Cre-GFP.4097, Tg(Itgax-cre,EGFP)4097Ach
Transgene: Tg(Itgax-cre,-EGFP)4097Ach  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe Itgax promoter and enchancer were used to drive cre expression in a pIRES2-EGFP-based plasmid. Two lines were created with line 4097 exhibiting greater expression than 4272 in dendritic cells. (J:123556)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Itgax     Summary of all recombinase alleles driven by Itgax.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Notes
Two lines were created with line 4097 exhibiting greater expression than 4272 in dendritic cells.
References
Original:  J:123556 Stranges PB, et al., Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity. Immunity. 2007 May;26(5):629-41
All:  45 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/11/2019
MGI 6.14
The Jackson Laboratory