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Lhx1tm4Bhr
Targeted Allele Detail
Nomenclature
Symbol: Lhx1tm4Bhr
Name: LIM homeobox protein 1; targeted mutation 4, Richard R Behringer
MGI ID: MGI:3719681
Synonyms: Lhx1fx1
Gene: Lhx1  Location: Chr11:84519379-84525534 bp, - strand  Genetic Position: Chr11, 51.31 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123471
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted into the first intron and a floxed neo cassette was inserted into the fourth intron. (J:123471)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lhx1 Mutation:  15 strains or lines available
References
Original:  J:123471 Zhao Y, et al., LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13182-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory