Ramp2tm1Kmca
Targeted Allele Detail
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Symbol: |
Ramp2tm1Kmca |
Name: |
receptor (calcitonin) activity modifying protein 2; targeted mutation 1, Kathleen Caron |
MGI ID: |
MGI:3718497 |
Synonyms: |
Ramp2- |
Gene: |
Ramp2 Location: Chr11:101137160-101139076 bp, + strand Genetic Position: Chr11, 64.47 cM
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Alliance: |
Ramp2tm1Kmca page
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Developmental cardiovascular defects in Ramp2tm1Kmca/Ramp2tm1Kmca embryos
Show the 4 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:123382
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Parent Cell Line: |
TC1/TC-1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The promoter region and exons 1 and 2 were replaced with the neomycin resistance cassette. Quantitative RT-PCR did not detect transcripts in mutant embryonic RNA extracts.
(J:123382)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Ramp2 Mutation: |
14 strains or lines available
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Original: |
J:123382 Dackor R, et al., Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age. J Biol Chem. 2007 Jun 22;282(25):18094-9 |
All: |
5 reference(s) |
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