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Tg(SOD1)51Yg
Transgene Detail
Nomenclature
Symbol: Tg(SOD1)51Yg
Name: transgene insertion 51, Yoram Groner
MGI ID: MGI:3718455
Synonyms: tg-SOD69
Transgene: Tg(SOD1)51Yg  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA 14.5 kb fragment of human genomic DNA containing the entire SOD1 gene, including its regulatory sequences, was used for microinjection into fertilized eggs. Line 51 contains 4-5 copies of the transgene and expresses 3-5-fold more superoxide dismutase 1in the brain than non-transgenic mice. (J:96742)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:96742 Harris-Cerruti C, et al., Functional and morphological alterations in compound transgenic mice overexpressing Cu/Zn superoxide dismutase and amyloid precursor protein [correction]. Eur J Neurosci. 2004 Mar;19(5):1174-90
All:  1 reference(s)

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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory