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Unc119tm1Gina
Targeted Allele Detail
Nomenclature
Symbol: Unc119tm1Gina
Name: unc-119 lipid binding chaperone; targeted mutation 1, George Inana
MGI ID: MGI:3718005
Gene: Unc119  Location: Chr11:78343482-78349164 bp, + strand  Genetic Position: Chr11, 46.74 cM, cytoband B5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123195
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe distal region of exon 1 and intron 1 were replaced with a neomycin resistance gene. A stop codon incorporated at the junction was used to prevent run-on translation. (J:123195)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Unc119 Mutation:  4 strains or lines available
References
Original:  J:123195 Ishiba Y, et al., Targeted inactivation of synaptic HRG4 (UNC119) causes dysfunction in the distal photoreceptor and slow retinal degeneration, revealing a new function. Exp Eye Res. 2007 Mar;84(3):473-85
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/11/2017
MGI 6.08
The Jackson Laboratory