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Itga2btm1Graf
Targeted Allele Detail
Nomenclature
Symbol: Itga2btm1Graf
Name: integrin alpha 2b; targeted mutation 1, Thomas Graf
MGI ID: MGI:3717592
Synonyms: CD41-YFPki
Gene: Itga2b  Location: Chr11:102453297-102469883 bp, - strand  Genetic Position: Chr11, 66.29 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:123159
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsA YFP gene was inserted right after the endogenous promoter. A floxed neo was included in the vector. (J:123159)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Itga2b Mutation:  0 strains or lines available
References
Original:  J:123159 Zhang J, et al., CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation. Exp Hematol. 2007 Mar;35(3):490-499
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory