About   Help   FAQ
Shc1tm9Paw
Targeted Allele Detail
Nomenclature
Symbol: Shc1tm9Paw
Name: src homology 2 domain-containing transforming protein C1; targeted mutation 9, Tony Pawson
MGI ID: MGI:3716783
Synonyms: ShcAflx
Gene: Shc1  Location: Chr3:89418443-89430015 bp, + strand  Genetic Position: Chr3, 39.11 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122927
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted into intron 1. The wild-type cDNA with a 3xFlag epitope tag-pA cassette was inserted into in exon 3. A neomycin resistance gene was inserted downstream of the cassette and loxP site. (J:122927)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Shc1 Mutation:  45 strains or lines available
References
Original:  J:122927 Hardy WR, et al., Combinatorial ShcA docking interactions support diversity in tissue morphogenesis. Science. 2007 Jul 13;317(5835):251-6
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/23/2015
MGI 5.22
The Jackson Laboratory