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Angptl4tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Angptl4tm1Lex
Name: angiopoietin-like 4; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3716688
Synonyms: Angptl4-
Gene: Angptl4  Location: Chr17:33773750-33781575 bp, - strand  Genetic Position: Chr17, 17.98 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122968
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A targeting vector was designed to replace exons 2 and 3 with a neomycin resistance gene. (J:122968)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Angptl4 Mutation:  17 strains or lines available
References
Original:  J:122968 Desai U, et al., Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11766-71
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory