Niban1^tm1Hin
Targeted Allele Detail

Summary

• Symbol: Niban1^tm1Hin
• Name: niban apoptosis regulator 1; targeted mutation 1, Okio Hino
• MGI ID: MGI:3716629
• Synonyms: Niban^-
• Gene: Niban1 Location: Chr1:151447124-151596791 bp, + strand Genetic Position: Chr1, 64.21 cM
• Alliance: Niban1^tm1Hin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123035
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 7 and 8 were replaced by a neomycin resistance cassette. Western blot confirmed absence of protein in mutant heart and muscle samples. (J:123035)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Niban1 Mutation: 65 strains or lines available

References

• Original: J:123035 Sun GD, et al., The endoplasmic reticulum stress-inducible protein Niban regulates eIF2alpha and S6K1/4E-BP1 phosphorylation. Biochem Biophys Res Commun. 2007 Aug 17;360(1):181-7
• All: 1 reference(s)