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Glultm2Whla
Targeted Allele Detail
Nomenclature
Symbol: Glultm2Whla
Name: glutamate-ammonia ligase (glutamine synthetase); targeted mutation 2, Wouter H Lamers
MGI ID: MGI:3715489
Synonyms: GSGFP
Gene: Glul  Location: Chr1:153899944-153909723 bp, + strand  Genetic Position: Chr1, 65.43 cM, cytoband G2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122377
Parent Cell Line:  IB10/E14IB10 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 to 6 were replaced with a GFP/laminA cassette to create a null allele. RT-PCR was done to confirm the altered transcript. (J:122377)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Glul Mutation:  24 strains or lines available
References
Original:  J:122377 He Y, et al., Glutamine synthetase is essential in early mouse embryogenesis. Dev Dyn. 2007 Jul;236(7):1865-75
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory