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Abcg1tm1Asch
Targeted Allele Detail
Nomenclature
Symbol: Abcg1tm1Asch
Name: ATP binding cassette subfamily G member 1; targeted mutation 1, A Schurmann
MGI ID: MGI:3715323
Synonyms: Abcg1-
Gene: Abcg1  Location: Chr17:31057694-31117984 bp, + strand  Genetic Position: Chr17, 15.8 cM, cytoband A2-B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:122438
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neo cassette was inserted into exons 3 and 5 replacing the intervening sequence. The absence of protein expression was confirmed by western blot analysis. (J:122438)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Abcg1 Mutation:  15 strains or lines available
References
Original:  J:122438 Buchmann J, et al., Ablation of the cholesterol transporter adenosine triphosphate-binding cassette transporter G1 reduces adipose cell size and protects against diet-induced obesity. Endocrinology. 2007 Apr;148(4):1561-73
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory